Introduction to Bromoacetonitrile
Bromoacetonitrile is a valuable organic compound widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Known for its high reactivity due to the presence of both a nitrile and bromine functional group, bromoacetonitrile plays an essential role in nucleophilic substitution reactions and various coupling processes.
With the chemical formula BrCH₂CN, it appears as a colorless to light yellow liquid and is highly soluble in most organic solvents. Despite its widespread application, it must be handled with care due to its toxic and irritant properties.
Chemical Properties of Bromoacetonitrile
Bromoacetonitrile contains both electrophilic (bromo) and electron-withdrawing (nitrile) groups, making it highly reactive for use in alkylation and functional group transformations.
| Property | Details |
|---|---|
| Chemical Formula | BrCH₂CN |
| Molecular Weight | 118.94 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | ~112–114°C |
| Density | 1.6 g/cm³ |
| Solubility | Miscible in organic solvents |
These properties make bromoacetonitrile a preferred intermediate in several synthetic pathways, particularly in pharmaceutical research.
Applications of Bromoacetonitrile in Industry
1. Pharmaceutical Manufacturing
Bromoacetonitrile serves as a key intermediate in the synthesis of heterocyclic compounds, which are fundamental in developing active pharmaceutical ingredients (APIs). Its versatility allows for use in the production of antiviral, anti-inflammatory, and anticancer agents.
2. Agrochemical Synthesis
It is also used in the preparation of pesticides, herbicides, and fungicides. The reactivity of bromoacetonitrile allows it to modify molecular frameworks and enhance the biological properties of agrochemical products.
3. Research and Development
In academic and industrial R&D laboratories, bromoacetonitrile is frequently employed in the development of novel organic compounds and the study of reaction mechanisms. Its well-defined chemical behavior provides a useful base for advanced synthesis.
Handling and Storage of Bromoacetonitrile
Due to its toxicity and potential health risks, bromoacetonitrile should only be handled by trained professionals in a controlled environment.
Safety Guidelines:
Use only in well-ventilated areas or fume hoods.
Wear protective clothing, gloves, and safety goggles.
Avoid direct skin and eye contact.
Store in tightly closed containers in a cool, dry, and well-ventilated space.
Refer to the MSDS (Material Safety Data Sheet) for detailed handling instructions and emergency measures.
Bromoacetonitrile Manufacturers in India & Europe
India and Europe host several reputable chemical manufacturers who specialize in producing high-quality bromoacetonitrile for global distribution. These manufacturers adhere to strict regulatory standards and offer reliable packaging, quality testing, and export services.
At Lifechem Pharma, we are proud to be a reliable supplier of bromoacetonitrile, serving clients across India, Europe, and beyond. Our products undergo rigorous quality checks, and we provide necessary documentation such as Certificates of Analysis (COA) and MSDS for safe handling and usage.
Why Choose Lifechem Pharma?
High-purity bromoacetonitrile with consistent batch quality
Competitive pricing and bulk availability
Fast delivery across India and European regions
Complete technical support and regulatory documentation
Trusted by pharmaceutical and chemical manufacturers globally
Conclusion
Bromoacetonitrile is an important building block in organic synthesis, especially in pharmaceutical and agrochemical industries. Its dual functional groups make it highly reactive and versatile for various chemical transformations. However, due to its toxic nature, proper handling and sourcing from trusted suppliers are critical.
Methyl carbazate is commonly used as a key intermediate in the synthesis of pharmaceutical compounds and heterocyclic derivatives.
