Profhilo in 2026: Everything to Know Before Choosing This Injectable Treatment
Skin aging is no longer only about wrinkles. In 2026, people care more about skin quality. Hydration, firmness, glow and elasticity now matter just as much as lines. This shift is the reason profhilo continues to grow in popularity across Europe, especially in the Netherlands.
Unlike traditional fillers that change shape or add volume, Profhilo focuses on improving how your skin behaves and feels. It works from the inside, helping skin act younger instead of just looking tighter.
This article explains what Profhilo is, how it works, what science says about it and what you should know before choosing this injectable treatment in 2026.
What Is Profhilo?
Profhilo is an injectable skin treatment made with pure hyaluronic acid. Hyaluronic acid is a substance already found in the human body. Its main job is to hold water and keep skin hydrated and elastic.
Profhilo was developed by IBSA Derma, a Swiss pharmaceutical company known for medical-grade hyaluronic acid research. According to IBSA Derma, Profhilo contains one of the highest concentrations of hyaluronic acid used in aesthetic medicine, without chemical cross-linking.
This is important because non-cross-linked hyaluronic acid spreads evenly under the skin instead of staying in one spot. That is why Profhilo is not considered a dermal filler.
How Profhilo Works Inside the Skin
Profhilo works through a process called bio-remodelling. Instead of filling wrinkles or reshaping the face, it improves skin quality on a deeper level.
After injection, Profhilo spreads under the skin and starts working in three main ways:
First, it deeply hydrates the skin. Hyaluronic acid binds water molecules, improving moisture from the inside out. This helps dry, tired-looking skin regain softness and glow.
Second, it stimulates collagen production. Collagen is the protein that gives skin structure and strength. Studies published on PubMed Central show that hybrid hyaluronic acid complexes like those used in Profhilo support fibroblast activity, which leads to new collagen formation.
Third, it boosts elastin production. Elastin helps skin stretch and return to its shape. As elastin decreases with age, skin starts to sag. Profhilo helps improve elasticity over time.
Why Profhilo Is Still Relevant in 2026
In 2026, patients are asking for natural results more than ever. Overfilled faces and frozen expressions are no longer trends. People want to look rested, healthy, and fresh.
Profhilo fits this demand because:
It does not add volume
It does not change facial features
It supports the skin’s natural repair system
According to clinical observations shared by aesthetic physicians in European journals, patients prefer treatments with subtle but real improvements. Profhilo meets this expectation by improving texture, firmness, and hydration without obvious signs of injectables.
Scientific Evidence Behind Profhilo
Profhilo is not just a trend. It is supported by clinical data.
A 2022 clinical study published on PubMed Central (PMC9509274) evaluated the effects of Profhilo on skin laxity and texture. The study reported visible improvement in skin firmness and hydration after two treatment sessions, with high patient satisfaction.
Another safety-focused review published in Dermatologic Therapy Journal confirmed that Profhilo has a strong safety profile when administered by trained professionals. Side effects were mild and temporary, mainly redness or small bumps at injection sites.
These findings support why Profhilo continues to be widely used in 2026.
Areas Where Profhilo Can Be Used
Profhilo is versatile. It is commonly used on:
The face, especially areas with fine lines and loss of elasticity.
The neck, where skin often becomes thin and crepey.
The décolleté, which shows early signs of sun damage and aging.
Hands, where volume loss and skin thinning are visible.
Body areas such as arms or knees, using Profhilo Body formulations.
This flexibility makes profhilo a popular skin booster rather than a targeted wrinkle treatment.
Who Is a Good Candidate for Profhilo?
Profhilo is suitable for both women and men. You may be a good candidate if:
Your skin feels dry even with good skincare.
You notice mild to moderate sagging.
Your skin looks dull or tired.
You want natural improvement without fillers.
According to aesthetic clinics in the Netherlands, Profhilo is often chosen by people in their late 20s to 60s. Younger patients use it for prevention and hydration, while older patients use it to improve firmness and texture.
The Treatment Process Explained
The Profhilo treatment is simple and quick.
A trained practitioner injects Profhilo into specific points known as BAP points (Bio Aesthetic Points). These points allow the product to spread evenly across the skin.
The session usually takes about 20 to 30 minutes. Most people do not need numbing cream because discomfort is minimal.
The standard protocol includes two sessions, spaced four weeks apart. This schedule is based on clinical recommendations from IBSA Derma and European aesthetic guidelines.
What to Expect After Treatment
After treatment, small bumps may appear at injection sites. These usually disappear within 24 hours as the product spreads under the skin.
There is little to no downtime. Most people return to normal activities the same day.
Hydration improvements can be noticed within days. Firmer skin and better elasticity develop gradually over four to eight weeks as collagen and elastin production increases.
For those considering treatment in the Netherlands, clinics such as profhilo providers emphasize realistic expectations and gradual improvement rather than instant transformation.
How Long Do Results Last?
Results typically last around six months. This can vary based on age, skin condition, and lifestyle factors such as smoking or sun exposure.
Maintenance treatments are usually recommended one to two times per year. In 2026, many clinics combine Profhilo with other treatments like microneedling or laser therapy for longer-lasting skin quality improvement.
Profhilo vs Dermal Fillers
It is important to understand the difference.
Dermal fillers add volume and shape. They are used for cheeks, lips, and jawlines.
Profhilo does not add volume. It improves skin quality.
According to aesthetic doctors writing in the Journal of Cosmetic Dermatology, Profhilo should be viewed as a skin remodeling treatment, not a replacement for fillers. Many patients use both, depending on their goals.
Safety and Side Effects
Profhilo is considered safe when performed by qualified professionals.
Common side effects include mild redness, swelling, or tenderness. These usually resolve quickly.
Because Profhilo uses pure hyaluronic acid without chemical cross-linking, the risk of allergic reactions is very low. This is supported by safety data published by IBSA Derma and independent clinical reviews.
Is Profhilo the Right Injectable Choice for You in 2026?
Profhilo remains a strong option in 2026 for people who value natural-looking results and healthier skin rather than dramatic changes. By improving hydration, firmness, and elasticity, it supports the skin’s natural structure without altering facial features.
Backed by scientific research and years of clinical use, Profhilo has proven to be a reliable injectable treatment when performed by qualified professionals. Its focus on skin quality instead of volume makes it especially suitable for those seeking subtle, long-term improvement.
Choosing an experienced practitioner who understands skin anatomy and correct injection techniques is essential to achieving safe and effective results. If your goal is firmer, more radiant skin with minimal downtime, Profhilo may be the right choice for you in 2026.
